Safety study of malapposition of the bio-corrodible nitrided iron stent <i>in vivo</i>

Abstract To evaluate the safety of stent malapposition corrodible nitride iron as biodegradable cardiovascular implants, a total 108 stents were implanted into abdominal aortas, iliac arteries, and artery bifurcations 36 New Zealand white rabbits separately. Each rabbit was with three stents. After follow-up period 3 months, no thrombus embolism found in local downstream vessels. And other adverse events occurred either. Stent strut covered by endothelial layer started to show signs degradation, while struts exposed bifurcated blood flow tissue rust particle on surface. Also, there traces thrombosis excess inflammation. The authors conclude that risk brought less than 9 months is acceptable.